偶联药物的连接子及其对药物性质的影响

偶联药物的连接子及其对药物性质的影响

参考文献:

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[3] Hamann, P. R. et al. Bioconjugate Chem., 2002, 13, 47.

[4] Bargh, J. D., et al. Cleavable linkers in antibody–drug conjugates, Chem. Soc. Rev. 2019, 48, 4361.

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[7] Su, D., et al. Linker Design Impacts Antibody-Drug Conjugate Pharmacokinetics and Efficacy via Modulating the Stability and Payload Release Efficiency. Front Pharmacol., 2021; 12, 68, 7926.

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